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Channel: Medical Xpress news tagged with:pancreatic
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Pancreatic cancer clue

Chronic pancreatitis (CP) is a predisposing condition for pancreatic ductal adenocarcinoma (PDAC), the most common and deadly cancer of the pancreas. However, the link between CP and PDAC is not known.

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Targeting cell division in pancreatic cancer

Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread. There is an urgent need to evaluate more therapeutic targets. The...

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From cradle to grave: postnatal overnutrition linked to aging

Researchers at Baylor College of Medicine have found a new answer to an old question: how can overnutrition during infancy lead to long-lasting health problems such as diabetes? The report, published...

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Dipeptidyl peptidase-4 inhibitors may up pancreatic disease risk

(HealthDay)—Use of dipeptidyl peptidase-4 inhibitors (DPP-4i) is associated with increased risks for pancreatitis and pancreatic cancer in patients with newly diagnosed type 2 diabetes, according to a...

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Exposing how pancreatic cancer does its dirty work

Pancreatic cancer is one of the most insidious forms of the disease, in which an average of only 9% of patients are alive five years after diagnosis. One of the reasons for such a dismal outcome is...

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Nerves could be key to pancreatic cancer spread

A couple of molecules that nerve cells use to grow during development could help explain why the most common pancreatic cancers are so difficult to contain and for patients to survive, a new study led...

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Discovery paves the way for earlier detection of type 1 disease

Type 1 diabetes, an autoimmune disease that typically emerges before the age of 20, wipes out the body's ability to produce insulin—a hormone that's essential to life. Diagnosis often comes after...

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Methylation of microRNA may be a new powerful biomarker for cancer

Researchers from Osaka University find a new way to distinguish individuals with early pancreatic cancer from healthy controls, representing a promising new metric in cancer diagnosis

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Drug designed to treat metastatic pancreatic cancer may help extend life

A drug developed by researchers at the Renaissance School of Medicine at Stony Brook University that targets enzymes involved in the development of pancreatic cancer cells is showing promise for...

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New guideline clarifies role of radiation therapy in pancreatic cancer treatment

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides recommendations on the use of radiation therapy to treat patients diagnosed with pancreatic cancer, including...

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Overcoming resistance in pancreatic cancer

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called...

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Compound may play role in halting panceatic cancer

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to...

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Study finds new way to make chemotherapy more effective against pancreatic...

Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to...

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UK urine test that can detect early-stage pancreatic cancer starts clinical...

A urine test that can detect early stage pancreatic cancer has reached the final stage of validation before being developed for use with patients.

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Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

A new discovery about pancreatic cancer sheds light on how the cancer fuels its growth and may help explain how promising cancer drugs work—and for whom they will fail.

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PML as potential treatment for pancreatic cancer

A recent study in The FASEB Journal identifies a new mechanism of pancreatic tumors' resistance to chemotherapeutic treatment. The mechanism involves the loss of function of promyelocytic leukemia...

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Engineering antibodies for diagnosis and immunotherapy

Professor John Whitelock is improving the smarts of antibodies and sending them into the extracellular area to outwit those clever cancer cells.

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New approach to pain treatment in diseases of the pancreas

One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic...

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Fungal invasion of pancreas creates cancer risk

Certain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds.

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Response rate to albumin-bound paclitaxel + gemcitabine + cisplatin among...

Adding a drug that targets a molecular vulnerability in pancreatic cancer could provide substantial benefit to patients, according to a clinical trial study by the HonorHealth Research Institute and...

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